Mounjaro safety and urgent help

Need emergency medical care in Japan?

If you have trouble breathing, sudden swelling of the face or throat, collapse, or lose consciousness, call 119 for an ambulance. Don't wait for a chat reply; tell the operator where you are and your symptoms.

Know before you use it.

Check who should not use it, what to tell your doctor, and where to get help.

Approved use in Japan

In Japan, Mounjaro (tirzepatide) is approved for the treatment of type 2 diabetes. It is not approved for weight loss in Japan. Approval of a different tirzepatide product does not apply to Mounjaro. The doctor decides whether this medicine is right for you.

Who can and can't use it

Do not use it if any of these apply

  • You have had an allergic reaction to any of its ingredients.
  • Type 1 diabetes, diabetic ketoacidosis, or diabetic coma or pre-coma.
  • You have a severe infection or need emergency care such as urgent surgery.
  • You are pregnant or might be pregnant (do not use it; talk to your doctor).

Tell your doctor before treatment

  • Severe digestive symptoms, a history of pancreatitis, bowel obstruction, or abdominal surgery, or eye disease caused by diabetes.
  • Breastfeeding, plans to become pregnant, or a planned procedure with anesthesia or deep sedation.
  • All medicines you use, including insulin, other diabetes medicines, birth control pills, and warfarin.

Do not use Mounjaro together with other tirzepatide products. Talk to your doctor before changing medicines.

Common symptoms

Nausea, vomiting, diarrhea: These can happen, especially when you start treatment or increase the dose. Constipation, stomach pain, indigestion, and decreased appetite are also listed as side effects.

If symptoms are hard to bear: Contact the prescribing doctor, and do not change your treatment on your own.

If you feel unwell

Ongoing severe stomach pain, especially with vomiting, may be a sign of pancreatitis. Stop using Mounjaro and see a doctor right away.

Do not ignore severe constipation with bloating or vomiting; yellowing of the whites of the eyes or skin, or fever with stomach pain; sweating, shaking, or reduced alertness; or ongoing vomiting or diarrhea. Chat is not an emergency service.

While traveling

Show the medicine's name and packaging to any doctor or pharmacist who helps you. Before you travel, check how to handle it and read our Taking it home guide.

About this information

Key safety information for Mounjaro ATEOS for Japan. For other risks and precautions, read the full patient medication guide. Sources checked: October 10, 2026. Japanese package insert: September 2026, 11th edition. Patient guide: June 2026.

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